Botryoid means having many rounded knobby 
outgrowths resembling a bunch of grapes, such as 
certain types of cancer. Cancer is an abnormal growth  
of new tissue characterized by uncontrolled growth of 
abnormally structured cells that have a more primitive 
form. An example is a botryoid sarcoma (aka sarcoma 
botryoides or botryoid rhabdomyosarcoma)  which is a 
type of cancer that can be seen in the nasopharynx, 
urinary bladder, female genitalia, and the common bile 
duct, usually in children under age 8. 
 
The nasopharynx is the part of the pharynx that lies above the soft palate. The pharynx 
is a passage that connects the back of the nose and mouth to the esophagus. The soft 
palate is the back part of the roof of the mouth. Bile ducts are tubes that allow bile to flow 
through it. Bile is a bitter, yellow-green substance released from the liver that carries 
away waste products.
Another example of a botryoid mass is a botryoid odontogenic cyst, which is a type of 
cyst present in the mouth that appears grape-like in structure. A cyst is an abnormal 
lump, swelling, or sac that contains fluid, a part solid material, or a gas, and is covered 
with a membrane. A membrane is a thin layer of flexible tissue that covers something. A 
picture of a botryoid cancer is shown above, which clearly shows the grape like form that 
these masses can take. Botryoid is also known as uviform and staphyline. Botryoid 
comes from the Greek word “botryoeides” meaning “like a bunch of grapes.”