A lower motor neuron (often abbreviated LMNs) is the 
part of a motor neuron (a type of nerve cell) that  
connects the brainstem and spinal cord (via the upper  
is an area in the lower part of the brain that connects it 
with the spinal cord.
 
Skeletal muscles are muscles that are connected at either or both arms or legs with the 
skeleton of the body. Upper motor neurons are nerve cells in the motor cortex (an area of 
the brain located in middle, top part of the brain) that help make up nerve paths within the 
brain and from the brain to the spine. 
Lower motor neurons are present in the spinal nerves, peripheral nerves (nerves outside 
of the brain or spinal cord), and anterior horn cells. Anterior horn cells are types of cells 
located in the spinal cord. 
movement/and or sensation can occur in addition to a loss of certain reflexes and the 
occurrence of various other signs and symptoms such as decreased muscle tone, 
weakness, fasciculations (small involuntary muscle contraction), decreased reflexes, and